Zoetis Simparica Trio for Dogs is an advanced, all-in-one protection solution designed to keep dogs healthy and parasite-free. This chewable tablet combines three powerful active ingredients to provide comprehensive protection against ticks, fleas, heartworms, and intestinal worms. Each pack contains three tablets, offering a three-month supply of continuous parasite control. Simparica Trio is suitable for dogs of all sizes, highly palatable, and easy to administer.
Composition: Sarolaner + Moxidectin + Pyrantel
Class: Anti-tick and flea chewable tablet
Active Ingredients and Functions:
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Sarolaner: Kills adult fleas and ticks, providing fast-acting ectoparasite control.
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Moxidectin: A macrocyclic lactone that prevents heartworm disease caused by Dirofilaria immitis.
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Pyrantel Pamoate: An anthelmintic that treats and controls roundworms and hookworms.
Dosage Based on Dog Weight:
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2.5–5 kg: Sarolaner 6 mg, Moxidectin 0.12 mg, Pyrantel 25 mg
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5–10 kg: Sarolaner 12 mg, Moxidectin 0.24 mg, Pyrantel 50 mg
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10–20 kg: Sarolaner 24 mg, Moxidectin 0.48 mg, Pyrantel 100 mg
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20–40 kg: Sarolaner 48 mg, Moxidectin 0.96 mg, Pyrantel 200 mg
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40–60 kg: Sarolaner 72 mg, Moxidectin 1.44 mg, Pyrantel 300 mg
Uses of Simparica Trio:
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Tick Control: Kills and controls multiple tick species including black-legged tick, Lone Star tick, and American dog tick.
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Flea Control: Starts killing fleas within 3 hours and provides a full month of protection.
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Heartworm Prevention: Prevents heartworm disease caused by Dirofilaria immitis.
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Intestinal Worm Treatment: Controls and treats roundworms and hookworms.
Benefits:
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Comprehensive Protection: Targets multiple parasites with a single monthly dose.
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Fast-Acting: Quickly eliminates fleas and ticks for immediate relief.
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Convenient: Combines three essential protections into one chewable tablet.
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Long-Lasting: Each tablet provides one month of protection, reducing frequent dosing.
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Safe and Effective: Clinically proven for dogs of all sizes.
Features:
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Triple-Action Formula: Combines sarolaner, moxidectin, and pyrantel pamoate for broad parasite coverage.
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Highly Palatable: Beef-flavored chewable tablets are easily accepted by dogs.
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Veterinarian Recommended: Trusted by veterinarians for comprehensive parasite protection.
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For All Breeds: Suitable for dogs of all breeds and sizes, with weight-based dosing.
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Pack of 3: Provides a three-month supply of protection.
Directions for Use:
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Dosage: Consult a veterinarian for the correct dosage based on your dog’s weight. Administer one chewable tablet once monthly.
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Administration: Give directly into your dog’s mouth or mix with a small amount of food to ensure complete consumption.
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Frequency: Administer monthly for continuous protection against ticks, fleas, heartworms, and intestinal worms.
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Monitoring: Regularly observe your dog’s health and response to the medication. Consult a veterinarian if concerns arise.
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Storage: Store in a cool, dry place away from sunlight. Keep the package tightly closed and out of reach of children and pets.
Precautions:
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Veterinary Guidance: Use under veterinary supervision, especially if your dog has pre-existing conditions or is on other medications.
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Age and Weight Restrictions: Not recommended for puppies under 8 weeks or dogs under 2.8 pounds.
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Adverse Reactions: Monitor for vomiting, diarrhea, lethargy, or other side effects and contact a veterinarian if observed.
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Not for Human Use: Intended solely for animal use.
Safety Information:
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Pregnancy and Lactation: Consult a veterinarian before use in breeding, pregnant, or lactating dogs.
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Side Effects: Rarely may include vomiting, diarrhea, lethargy, anorexia, or itching. Seek veterinary advice if observed.
Disclosure:
A licensed vendor partner will deliver this medicine. Pharmacy details will be shared once the order is accepted. Order acceptance depends on the validity of your veterinarian’s prescription and product availability.
Disclaimer:
Fifozone provides expert-reviewed, accurate, and trustworthy information. This content is for informational purposes only and should not replace professional veterinary advice. Consult your veterinarian for personalized guidance regarding your dog’s health. Fifozone supports, but does not replace, the veterinarian-client relationship.

















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