Vivaldis Grapitail 100mg (Grapiprant) Tablet for Dogs

Vivaldis Grapitail 100mg (Grapiprant) Tablet for Dogs

Grapitail for dogs is a prescription tablet that relieves the pain and inflammation of osteoarthritis, the most common cause of chronic joint pain and limping in dogs. Its active ingredient is grapiprant, a newer type of anti-inflammatory that targets pain more selectively than traditional NSAIDs, which can make it gentler on the stomach and kidneys. Grapitail is the Indian made version of the molecule sold internationally as Galliprant, at a more accessible price. Available in packs of 6, 12 and 24 tablets, with the Grapitail 100mg price starting at Rs 1,010 per strip.

Composition : Grapiprant

Class: Non-steroidal anti-inflammatory drug

What Grapitail is and how it works?

Grapitail contains grapiprant 100mg, which belongs to a class of drugs called piprants. Unlike traditional NSAIDs that block the COX enzymes broadly, grapiprant works by blocking just one specific receptor, the EP4 receptor, which is the main receptor responsible for the pain and inflammation of osteoarthritis. Because it acts more selectively, it targets arthritis pain while having less effect on the pathways that protect the stomach lining and kidneys. That selectivity is the reason many vets choose it for long term arthritis management, especially in older dogs.

It is important to understand what this means in practice. Grapiprant for dogs is a genuine anti inflammatory pain reliever, not a joint supplement and not a sedative. It reduces the pain your dog is feeling so they can move more comfortably, but it works best as part of a full arthritis plan that also includes weight management, controlled exercise and often a joint supplement alongside it.

What Grapitail is used for?

Vets prescribe Grapitail mainly for the pain and inflammation of osteoarthritis. The common signs it helps with include:

• Stiffness, especially after rest or first thing in the morning

• Limping or favouring a leg, and not putting full weight on a limb

• Reluctance to jump, climb stairs, or go for walks they used to enjoy

• Slowing down, sleeping more, or seeming grumpy when touched on a sore joint

• General decline in mobility that comes with ageing or hip dysplasia

If your dog is showing these signs, they should be examined by a vet, who can confirm osteoarthritis and decide whether Grapitail is right for them. See our guide to managing arthritis in dogs for the fuller picture.

Grapitail dosage for dogs by weight

Grapiprant is dosed by body weight, and your vet will confirm the exact dose and how long to give it. As a general guide, the standard dose is approximately 2mg per kg of body weight, given once daily. Each Grapitail tablet is 100mg.

• Give once daily, ideally at the same time each day so it is easy to remember.

• With or without food. Grapiprant can be given on an empty stomach or with a small meal. Some vets suggest giving it at least one hour before or two hours after food, so follow your vet’s specific instruction.

• Do not adjust the dose yourself. Never increase the dose or give it more often than prescribed, even if your dog still seems sore, as that raises the risk of side effects.

• Do not combine with other NSAIDs or steroids unless your vet specifically directs it, as this significantly increases the risk of harm.

How long does Grapitail take to work?

Many dogs show some improvement in comfort and movement within the first few days, though the full benefit for chronic arthritis builds over one to two weeks of daily dosing. Because arthritis is a long term condition, Grapitail is often given over extended periods under veterinary supervision, with periodic check ups. If you see no improvement after two weeks of correct dosing, go back to your vet rather than increasing the dose, as the treatment plan may need adjusting.

Safety information and side effects

Grapiprant is generally well tolerated, and its selective action means it is often chosen for dogs who need long term pain relief. As with any anti inflammatory, side effects are possible and worth knowing.

Common side effects

The most commonly reported effects are mild and digestive: occasional vomiting, soft stool or diarrhoea, and reduced appetite, usually early in treatment. Giving the tablet consistently and keeping your vet informed usually keeps these manageable.

When to stop and call your vet?

• Repeated vomiting or diarrhoea, especially if there is any blood, or black tarry stool

• A clear drop in appetite, unusual tiredness, or yellowing of the eyes or gums

• Any sudden change in drinking, urination or behaviour

These can signal a more serious reaction, so stop the medicine and contact your vet promptly if you see them. For quick guidance, book a Fifozone Online Vet Consultation. If your pet needs an in-person examination, diagnostics, or urgent follow-up, visit a Fifozone+ Clinic in Bengaluru or book an appointment

Do not give Grapitail if

• Your dog is pregnant, lactating, or intended for breeding, as safety has not been established

• Your dog is younger than the minimum age or below the minimum weight your vet advises

• Your dog has a known sensitivity to grapiprant

• Your dog is already on another NSAID or a corticosteroid, unless your vet has specifically planned the transition

• Your dog has significant liver, kidney or gastrointestinal disease, without specific veterinary guidance

Tell your vet about any other medicines your dog is taking, and about any existing health conditions, before starting Grapitail.

Grapitail vs Galliprant, and vs traditional NSAIDs

Two comparisons come up a lot, so here is the honest picture.

Grapitail vs Galliprant

They are the same molecule, grapiprant. Galliprant is the internationally known brand, and Grapitail is an Indian manufactured version of the same active ingredient, which makes it more accessible and affordable for Indian pet parents. Your vet can advise whether the generic is appropriate for your dog, and in most cases the active ingredient and its action are the same.

Grapiprant vs meloxicam or carprofen

Meloxicam and carprofen are traditional NSAIDs that block the COX enzymes more broadly. They are effective and widely used, but that broader action is why they carry a stomach and kidney caution, particularly for long term use in older dogs. Grapiprant’s selective, EP4 targeted action is often preferred where a dog needs sustained arthritis relief or has tolerated traditional NSAIDs poorly. Neither is universally better, and the right choice depends on your individual dog, which is a decision for your vet. Fifozone stocks the alternatives too, including Vivaldis Firotail firocoxib and Intas Melonex meloxicam, within the full dog pain relief range.

Substitutes and alternatives

If your vet recommends a different approach, these are the closest options on Fifozone.

Storage and handling

• Store below 30 degrees C in a dry place, away from direct sunlight.

• Keep tablets in the original strip until use, so batch and expiry stay visible.

• Keep well out of reach of children and pets. Accidental ingestion of a pain medicine needs urgent attention.

• Do not use past the printed expiry.

Why buy Grapitail from Fifozone?

Prescription handled fast. Grapitail is a Schedule H prescription medicine, so a valid prescription is required. Upload yours at checkout, or order and our team verifies it quickly, and a Fifozone vet can issue one on a call if needed. For a dog starting long term arthritis medication, that vet oversight matters, and the Fifozone Clinic can examine your dog and set up the right plan.

100% genuine Vivaldis stock, sourced through authorised channels with batch and expiry you can verify against the pack. Counterfeit medicines are a real risk in the Indian market.

Fast delivery. 24-hour delivery across Indian cities, with 30-minute delivery in parts of metro cities. Free shipping on orders above the threshold. Browse the wider dog pharmacy and arthritis ranges.

A note on returns: as a pharmacy item, Grapitail is non-returnable and non-exchangeable once dispatched. If your order arrives damaged, incorrect or short dated, call 1800-5723-575 and we will replace it.

Help your dog move comfortably again. Order vet-prescribed Grapitail (grapiprant) for arthritis pain from Rs 1,010, with a vet consult to confirm the right dose and your prescription handled quickly!

FAQs

What is Grapitail used for in dogs?

Grapitail is used to relieve the pain and inflammation of osteoarthritis in dogs, the main cause of chronic joint pain, stiffness and limping. It contains grapiprant, a selective anti inflammatory. It helps dogs move more comfortably and is used as part of an arthritis plan under veterinary guidance, not as a one off painkiller.

What is the grapiprant dosage for dogs?

The usual dose is about 2mg per kilogram of body weight, once daily, and each Grapitail tablet is 100mg. Your vet calculates the exact dose for your dog’s weight and confirms how long to give it. Give it once a day at the same time, and never increase the dose yourself, even if your dog still seems sore.

How long does Grapitail take to work?

Many dogs are more comfortable within the first few days, with the fuller benefit building over one to two weeks of daily use. Because arthritis is long term, it is often continued under veterinary supervision. If there is no improvement after two weeks of correct dosing, see your vet rather than increasing the dose.

Should Grapitail be given with food or on an empty stomach?

Grapiprant can be given with or without food. Some vets advise giving it at least an hour before or two hours after a meal, so follow your vet’s specific instruction. Giving it at the same time each day makes it easier to remember and keeps the effect steady.

What are the side effects of Grapitail?

The most common side effects are mild and digestive, such as occasional vomiting, soft stool or reduced appetite, usually early on. Stop the medicine and contact your vet if you see repeated vomiting or diarrhoea, any blood or black stool, yellowing of the eyes or gums, or unusual tiredness, as these can signal a more serious reaction.

Can I give Grapitail without a vet prescription?

No. Grapitail is a Schedule H prescription medicine, so a vet prescription is required by law, and it should only be given after a vet has diagnosed osteoarthritis. You can upload a prescription at checkout, or our vet can issue one after a consultation. Giving a pain medicine without a diagnosis can hide a more serious problem.

Is Grapitail the same as Galliprant?

Both contain the same active ingredient, grapiprant. Galliprant is the internationally known brand, and Grapitail is an Indian manufactured version of the same molecule, which makes it more affordable. In most cases the active ingredient and how it works are the same, and your vet can confirm the generic is suitable for your dog.

How is grapiprant different from meloxicam or carprofen?

Meloxicam and carprofen are traditional NSAIDs that block the COX enzymes broadly, while grapiprant targets just the EP4 receptor behind arthritis pain. That selective action means grapiprant can be gentler on the stomach and kidneys, which is why it is often chosen for long term use in older dogs. The best choice depends on your dog, so ask your vet.

Disclaimer: Fifozone’ sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.